Pmx and gromacs for lprotein-ligand

1

Dear All: I know there is good instruction on how to do FEP for two ligands and evaluate the free energy difference. It will be a great help if some one can revisit this in some more detail including the full steps to do the tutorials in some more details including all steps. May be I am missing something to complete the tutorial and stuck after doing the energy minimization. Thanks a lot