Solvated docking without defining Active or Passive residues

HADDOCK
1

Hi
Is there any way I can dock a protein and nucleic acid without defining any active or passive residues?
Random AIRs and Centre of Mass restraints are not working for solvated docking. Is there any similar platform where I can get the job done?

Thank you in advance

2

Solvated docking only makes sense if you have good data.

Without it simply use centre of mass or random airs.

3

Thank you for the response.