I was going through the haddock webinar recently and if im not wrong, what i understand is that it’s necessary to input active and passive residues.
My work involves identifying protein hotspots that result in protein self-aggregation. As there is no literature on the particular residues that are involved in this process, im unable to input these active/passive residues.
I did notice that the webinar also mentioned something about protein-protein docking using solvent accessible surface area.
Is this available in haddock 2.2 or 2.4? Im not able to find the specific function in both.
Would appreciate it if anyone can point me in the right direction. Thanks!