how to interpret results when Haddock score is positive but the binding affinity from prodigy is negative
Score is not binding affinity…
And look at the components of the score to understand where the positive value comes from.
Most likely still high restraint energy…
so they can be considered a good result or not? and what is meaning of high restraint energy how to interpret it in results
are results bad when restraint energy is high
High restraint energy means your models are not satisfying the information you gave to HADDOCK.
It all depends on how good that information was…
You can always calculate the score without the restraint energy (subtract 10% of the restraint energy).
Or refine the models through our refinement interface.
are results bad when haddock score is positive or restraint violation energy is high?