If I were to choose one best mutation between two, mutation A has better HADDOCK Score but mutation B has better binding affinity obtained from PRODIGY, which aspect should I prioritize in choosing the best mutation?
Related topics
| Topic | Replies | Views | Activity | |
|---|---|---|---|---|
| HADDOCK Score vs PRODIGY binding affinity in the case of mutations | 1 | 254 | December 12, 2023 | |
| Challenges in Consistency: Comparing Mutated Protein Forms with Wild-Type Using Haddock | 1 | 42 | June 19, 2024 | |
| Validity of Comparing Binding Energies for a Series of Mutations in a Native Peptide | 3 | 628 | July 1, 2020 | |
| A difference in HADDOCK scores, RMSD and Z-scores for the identical protein-protein complex run multiple times | 5 | 1108 | November 16, 2020 | |
|
HADDOCK score vs. Prodigy Binding energy?
|
1 | 312 | October 14, 2022 |