Can I partially unfold RNA for docking?

HADDOCK
1

Hi,
I would like to perform some RNA-Protein docking.
Is there a way to unfold my RNA at the 3’-end?

Thank you!

Vanessa

2

I would like to perform some RNA-Protein docking.
Is there a way to unfold my RNA at the 3’-end?

What do you mean exactly?

Don’t expect large conformational changes during the docking.
So better to do it beforehand if you need it.

1 Like