PyMOL Mutagenesis

Hello! Is the PyMOL mutagenesis feature good to use in HADDOCK? I would like to test if my active residues will be defective in my protein-protein docking if mutated to hydrophobic amino acids, by determining the changes in binding affinity using PRODIGY. Is this possible?

You could run the refinement server on your mutated complex.

Note that prodigy was not trained to predict ddG