No correlation between score and binding affinity

HADDOCK
1

Hi,

I would like to know the titles of your published papers regarding that there is no correlation between haddock scores and binding affinity.

Best,
vafa

2

• P. Kastritis and A.M.J.J. Bonvin Are scoring functions in protein-protein docking ready to predict interactomes? Clues from a novel binding affinity benchmark. J. Proteome Research, 9, 2216-2225 (2010). https://doi.org/doi:10.1021/pr9009854

And related reviews:

• P.L. Kastritis and A.M.J.J. Bonvin Molecular origins of binding affinity: Seeking the Archimedean point. Curr. Opin. Struct. Biol., 23, 868-877 (2013).

• P.L. Kastritis and A.M.J.J. Bonvin On the binding affinity of macromolecular interactions: daring to ask why proteins interact J. R. Soc. Interface, 10, doi: 10.1098/rsif.2012.0835 (2013)

3

Thanks dear Dr. Bonvin.