Interacting on unstructured region


I have a two protein with their respective PDBs and I suspect that the bromo-binding domain of one binds onto the unstructured tail of the other. This unstructured tail of interest, is not part of the PDB. Can I still predict this interaction?

Thank you,

No tail no interaction I would say…

And if the interaction is with the disordered tail, rather only model that part - no need to use the full protein. This is then a protein-peptide docking case

Relevant info for this scenario: