How to choose a symmetry for a ab initio dimer docking?


I am trying to perform a ab-initio docking of a dimer but I do not know the kind of symmetry that it could have. Which selection of symmetry restraints would be the best then?

Thank you for your time.

If it is a homodimer, then I would expect then C2 symmetry

And also NCS symmetry between the chains.

Next to CM restraints

thank you for the answer. How many pairs of symmetry restraints would it be recommended to define for the homodimer?

Just one :slight_smile:

More would be redundant