DisVis web portal 2.0

In connection with the publication of the DisVis and PowerFit webserver in the Journal of Molecular Biology (“The DisVis and PowerFit web servers: Explorative and Integrative Modeling of Biomolecular Complexes” in press) we have made extensive changes to the DisVis web server Including:

  • Support of the occupancy analysis feature (new feature in DisVis 2.0)
  • Support of the residue-based interaction analysis (new feature in DisVis 2.0)
  • Improved post-processing and result presentation (colour highlighting, case-dependant messages, etc.)
  • Extended information on the help/manual page
  • More detailed examples
  • mmCIF support

See for yourself at http://milou.science.uu.nl/services/DISVIS/

The DisVis support team

We are glad to announce the release of our DISVIS webserver.

DisVis allows you to visualizes and quantify the information content of distance restraints between macromolecular complexes. It performs a full and systematic 6 dimensional search of the three translational and rotational degrees of freedom to determine the number of complexes consistent with the restraints. In addition, it outputs the percentage of restraints being violated and a density that represents the center-of-mass position of the scanning chain corresponding to the highest number of consistent restraints at every position in space.

In the context of integrating modelling, this tool should be particularly useful to assess the information content and reliability of cross-links detected by mass spectrometry.

Read more in the original publication.

DISVIS is also freely available for local installation through our GitHub repository: https://github.com/haddocking/disvis

The DISVIS web server is powered by the EGI grid resources.

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