- Is it possible to dock a DNA PDB to a protein with 2 chains? I am trying to do so after i used pdb_tidy from pdb tools but i am getting a RuntimeError(reason). Should i combine the 2 chains and if so how can i do it ?
The forum is searchable
E.g. https://ask.bioexcel.eu/t/dealing-with-dimers/42
In short you will have to make your dimer a single chain with non-overlapping residue numbering.
Also described for example in:
[
Low-sampling antibody-antigen modelling tutorial using a local version of HADDOCK3
bonvinlab.org
](Low-sampling antibody-antigen modelling tutorial using a local version of HADDOCK3 – Bonvin Lab)
and
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