Protein-protein docking parameters

Negin
Mon, 30 Jun 2025 23:57:16 +0000
HADDOCK

Hello
I would like to perform protein-protein docking, and I do not have any experimental data showing how they are interacting and what is the binding interface of them. But, I used PesTo webserver and other online tools to identify the active residues for input in HADDOCK docking webserver. Now, I am in the 3rd step (Docking parameters). I just have a couple of questions. Do you recommend applying any restraints for my system (such as center-of-mass? I do not know which parameters should be True and marked for my aim?
Please guide me though that.

3 posts - 3 participants