# %XXNXTFI-ERR: invalid or unknown path-name: "RUN" **URL:** \ **Category:** HADDOCK\ **Created:** [June 1, 2021, 10:49am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019 "2021-06-01T10:49:04Z")\ **Posts on this page:** 7\ **Page:** 1
**Author:** ![emartis12](https://avatars.discourse-cdn.com/v4/letter/e/439d5e/32.png) [@emartis12](https://ask.bioexcel.eu/u/emartis12)\ **Post date:** [June 1, 2021, 10:49am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/1 "2021-06-01T10:49:04Z")
Dear All @amjjbonvin Hello I am running haddock2.4 from local installation and the installation process was pretty smooth. However, I ran into an error while running run.cns which points to another file (./protocols/initialize.cns) that seems to exist. I am unable to resolve it. Here is the error message: CNSsolve\> CNSsolve\>@RUN:protocols/initialize.cns(iteration=$iteration;) %XXNXTFI-ERR: invalid or unknown path-name: “RUN”: @RUN:protocols/initialize.cns( ^^^^^^^^^^^^^^^^^^^^^^^^^^^^ %ASSFIL-ERR: error opening file RUN:protocols/initialize.cns %ASSFIL error encountered: Error accessing file (CNS is in mode: SET ABORT=NORMal END) * * * ABORT mode will terminate program execution. * * * Program will stop immediately. ---
**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\ **Post date:** [June 1, 2021, 11:48am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/2 "2021-06-01T11:48:51Z")
Did you follow our online tutorial for the local installation? ``` https://www.bonvinlab.org/education/HADDOCK24/HADDOCK24-local-tutorial/ ``` Are you able to run any of the examples or tests? ---
**Author:** ![emartis12](https://avatars.discourse-cdn.com/v4/letter/e/439d5e/32.png) [@emartis12](https://ask.bioexcel.eu/u/emartis12)\ **Post date:** [June 1, 2021, 12:57pm UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/3 "2021-06-01T12:57:03Z")
> [@amjjbonvin](#): > > `https://www.bonvinlab.org/education/HADDOCK24/HADDOCK24-local-tutorial/` Thanks for the prompt reply. The local installation was successful and as mentioned in the tutorial. I am unable to run the examples as well, the same error pops up. ---
**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\ **Post date:** [June 1, 2021, 1:13pm UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/4 "2021-06-01T13:13:23Z")
Then something is wrong with your setup… It can’t be successful if you can’t run the examples or tests. Are you sourcing the haddock\_configure.csh/sh script first? Describe exactly all steps you are doing until this error message pops up (i.e. exact commands you are giving) ---
**Author:** ![emartis12](https://avatars.discourse-cdn.com/v4/letter/e/439d5e/32.png) [@emartis12](https://ask.bioexcel.eu/u/emartis12)\ **Post date:** [June 2, 2021, 4:37am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/5 "2021-06-02T04:37:55Z")
Hello @amjjbonvin _Then something is wrong with your setup…_ _It can’t be successful if you can’t run the examples or tests._ You are right. This is something I noticed when I reinstalled haddock2.4. I perhaps missed to see this the first time. This is how is tried installing after I compiled cns3.1 ./install.csh config.local Setting up QueueSubmit to QueueSubmit\_concat.py fatal: not a git repository (or any of the parent directories): .git \>\>\>\>\>\> perhaps something not right? fatal: not a git repository (or any of the parent directories): .git \>\>\>\>\>\> perhaps something not right? Now compiling HADDOCK utilities cd tools;make make[1]: Entering directory ‘/opt/haddock2.4/tools’ make cluster\_struc contact contact-chainID haddock-decompress-fastfunc contact\_fcc contact\_fcc\_lig make[2]: Entering directory ‘/opt/haddock2.4/tools’ make[2]: ‘cluster\_struc’ is up to date. make[2]: ‘contact’ is up to date. make[2]: ‘contact-chainID’ is up to date. make[2]: ‘haddock-decompress-fastfunc’ is up to date. make[2]: ‘contact\_fcc’ is up to date. make[2]: ‘contact\_fcc\_lig’ is up to date. make[2]: Leaving directory ‘/opt/haddock2.4/tools’ make[1]: Leaving directory ‘/opt/haddock2.4/tools’ HADDOCK2.4 configured to use it source first haddock\_configure.csh/sh _Are you sourcing the haddock\_configure.csh/sh script first?_ Yes, before every run I would source haddock\_configure.csh. Describe exactly all steps you are doing until this error message pops up (i.e. exact commands you are giving) **step 1** \> Cleaning all the pdb files as mentioned in the basic tutorial for protein-protein docking. a) Remove chain ID and SEQ ID: pdb\_chain | pdb\_seg \>\ b) validate: pdb\_validate c) Find gaps: pdb\_gap d) define restrains between chains in case of more than 1 units: restrain\_bodies.py \>unambig.tbl c) Filter passive residues by SASA using freesasa: freesasa --format=rsa \>.rsa **Step 2** \> Generate restaints files from active and passive residues: active-passive-to-ambig.py rec-act- pass.txt lig-act-pass.txt \>rec-lig-ambig.tbl **Step3\>** prepare the run.param file. The contents are as follows: AMBIG\_TBL=rec-lig-ambig.tbl HADDOCK\_DIR=/opt/haddock2.4 N\_COMP=2 PDB\_FILE1=rec.pdb PDB\_FILE2=lig.pdb PROJECT\_DIR=./ PROT\_SEGID\_1=A PROT\_SEGID\_2=B RUN\_NUMBER=1 UNAMBIG\_TBL=unambig.tbl **Step4** \> source haddock\_configure.csh and then run the haddock2.4 command. It runs without any errors and creates a “run1” directory. **Step 5** \> run the haddock2.4 command in the run1 directory. And this is the step I am getting the error. Thanks Once again ---
**Author:** ![emartis12](https://avatars.discourse-cdn.com/v4/letter/e/439d5e/32.png) [@emartis12](https://ask.bioexcel.eu/u/emartis12)\ **Post date:** [June 2, 2021, 5:34am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/6 "2021-06-02T05:34:50Z")
Hello @amjjbonvin The problem was the faulty installation of cns. And once I reinstall compiled it, there was no problem. The examples are running running file. Thank you!! ---
**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\ **Post date:** [June 2, 2021, 6:13am UTC](https://ask.bioexcel.eu/t/xxnxtfi-err-invalid-or-unknown-path-name-run/3019/7 "2021-06-02T06:13:57Z")
Perfect - problem solved! :-))