# Run.param difficulties

**URL:** <https://ask.bioexcel.eu/t/run-param-difficulties/3281>\
**Category:** HADDOCK\
**Created:** [October 6, 2021, 3:26am UTC](https://ask.bioexcel.eu/t/run-param-difficulties/3281 "2021-10-06T03:26:37Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![yang1](https://avatars.discourse-cdn.com/v4/letter/y/bc8723/32.png) [@yang1](https://ask.bioexcel.eu/u/yang1)\
**Post date:** [October 6, 2021, 3:26am UTC](https://ask.bioexcel.eu/t/run-param-difficulties/3281/1 "2021-10-06T03:26:37Z")

</div>

hello , all , I have the difficuties with haddock . I have output the commands and this is the run.param file

HADDOCK\_DIR=…/…/  
N\_COMP=2  
PDB\_FILE1=./anas\_platyrhynchos\_B\_.pdb  
PDB\_FILE2=./anas\_platyrhynchos\_E\_.pdb  
PROJECT\_DIR=./run1  
PROT\_SEGID\_1=B  
PROT\_SEGID\_2=E  
RUN\_NUMBER=1

when I have source the haddock\_configure.csh and input haddock2.4 , the output shows that :

Traceback (most recent call last):  
File “/home/yjx/software/haddock2.4-2021-05/Haddock/RunHaddock.py”, line 153, in   
new[‘CRYO-EM\_FILE’],  
File “/home/yjx/software/haddock2.4-2021-05/Haddock/Main/Setup.py”, line 203, in SetupNewProject  
shutil.copy(Haddockdir+"/Haddock/CNS/KeepAlive.py", runDir + ‘/protocols’)  
File “/usr/lib/python2.7/shutil.py”, line 139, in copy  
copyfile(src, dst)  
File “/usr/lib/python2.7/shutil.py”, line 96, in copyfile  
with open(src, ‘rb’) as fsrc:  
IOError: [Errno 2] No such file or directory: ‘…/…/Haddock/CNS/KeepAlive.py’

what should I do to deal with the error ?