# Refinement interface query

**URL:** https://ask.bioexcel.eu/t/refinement-interface-query/2003
**Category:** HADDOCK
**Created:** [May 8, 2020, 7:46am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003 "2020-05-08T07:46:36Z")
**Posts on this page:** 5
**Page:** 1

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### Author: ![help\_me](https://avatars.discourse-cdn.com/v4/letter/h/958977/32.png) [@help\_me](https://ask.bioexcel.eu/u/help_me)
#### Post date: [May 8, 2020, 7:46am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003/1 "2020-05-08T07:46:36Z")

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Hi,  
Just a beginner’s query. If the restraints violation energy of my complex is high and has poor water coverage, will using the refinement interface on haddock improve upon it in this regard?

Thanks

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### Author: ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)
#### Post date: [May 8, 2020, 7:58am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003/2 "2020-05-08T07:58:04Z")

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The refinement interface does not use any restraints. So the restraint energy will be 0

And what do you mean by poor water coverage?

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### Author: ![help\_me](https://avatars.discourse-cdn.com/v4/letter/h/958977/32.png) [@help\_me](https://ask.bioexcel.eu/u/help_me)
#### Post date: [May 8, 2020, 8:20am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003/3 "2020-05-08T08:20:21Z")

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Thanks a lot for your reply. Sorry for the poor phrasing, I meant the percentage representation of the models generated in the third (water) iteration on HADDOCK.

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### Author: ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)
#### Post date: [May 8, 2020, 8:46am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003/4 "2020-05-08T08:46:38Z")

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Percentage of clustering? Number of models?

Refinement if starting from one model, will generate only one cluster

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### Author: ![help\_me](https://avatars.discourse-cdn.com/v4/letter/h/958977/32.png) [@help\_me](https://ask.bioexcel.eu/u/help_me)
#### Post date: [May 8, 2020, 9:46am UTC](https://ask.bioexcel.eu/t/refinement-interface-query/2003/5 "2020-05-08T09:46:28Z")

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Got it, thanks a lot.
