# Protein-DNA docking-advice required

**URL:** <https://ask.bioexcel.eu/t/protein-dna-docking-advice-required/1812>\
**Category:** HADDOCK\
**Created:** [January 29, 2020, 10:12am UTC](https://ask.bioexcel.eu/t/protein-dna-docking-advice-required/1812 "2020-01-29T10:12:10Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![rakeshmbb](https://avatars.discourse-cdn.com/v4/letter/r/d78d45/32.png) [@rakeshmbb](https://ask.bioexcel.eu/u/rakeshmbb)\
**Post date:** [January 29, 2020, 10:12am UTC](https://ask.bioexcel.eu/t/protein-dna-docking-advice-required/1812/1 "2020-01-29T10:12:10Z")

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I want to dock my protein with a DNA molecule. COACH server was used to define active residue in protein. How can I define active residue in DNA? Please tell me how to write active residue in HADDOCK web server?

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**Author:** ![honoratorv](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/honoratorv/32/672_2.png) [@honoratorv](https://ask.bioexcel.eu/u/honoratorv)\
**Post date:** [January 29, 2020, 10:31am UTC](https://ask.bioexcel.eu/t/protein-dna-docking-advice-required/1812/2 "2020-01-29T10:31:17Z")

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The way to define restraints is the same for all molecules, but make sure to select the correct type.

You can find more information about it on the basic tutorial: [http://www.bonvinlab.org/education/HADDOCK24/HADDOCK24-protein-protein-basic/#definition-of-restraints](http://www.bonvinlab.org/education/HADDOCK24/HADDOCK24-protein-protein-basic/#definition-of-restraints)

🙂