# PRODIGY-Hi. Is PRODIGY supported protein-RNA and protein-DNA complexes (because of comparing binding affinity)?

**URL:** <https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266>\
**Category:** HADDOCK\
**Created:** [January 8, 2017, 7:59am UTC](https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266 "2017-01-08T07:59:25Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![f.namazifar706938](https://avatars.discourse-cdn.com/v4/letter/f/8491ac/32.png) [@f.namazifar706938](https://ask.bioexcel.eu/u/f.namazifar706938)\
**Post date:** [January 8, 2017, 7:59am UTC](https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266/1 "2017-01-08T07:59:25Z")

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Hi. Is PRODIGY supported protein-RNA and protein-DNA complexes (because of comparing binding affinity)?

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**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\
**Post date:** [January 8, 2017, 9:33am UTC](https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266/2 "2017-01-08T09:33:22Z")

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See [BioExcel Webinar #7: PRODIGY, a web server to predict binding affinities in protein-protein complexes](https://ask.bioexcel.eu/t/bioexcel-webinar-7-prodigy-a-web-server-to-predict-binding-affinities-in-protein-protein-complexes/214/8?u=amjjbonvin)

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**Author:** ![f.namazifar706938](https://avatars.discourse-cdn.com/v4/letter/f/8491ac/32.png) [@f.namazifar706938](https://ask.bioexcel.eu/u/f.namazifar706938)\
**Post date:** [January 13, 2017, 8:32pm UTC](https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266/3 "2017-01-13T20:32:49Z")

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many thanks. and what’s your suggestion?

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**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\
**Post date:** [January 14, 2017, 12:49pm UTC](https://ask.bioexcel.eu/t/prodigy-hi-is-prodigy-supported-protein-rna-and-protein-dna-complexes-because-of-comparing-binding-affinity/266/4 "2017-01-14T12:49:20Z")

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No real suggestions at this time I am afraid…  
Binding affinity prediction is a hard problem. But do let us know if you find a method that works.