Is Torsion Angle Dynamics used in HADDOCK a MD- or MC-based conformational sampling?

Dear all,

Failed to find the details in the literature, I wonder that the torsion angle dynamics used in it1 is done by molecular dynamics simulations or Metropolis Monte Carlo? I’d guess it is by MD but just want to make sure. Thanks in advance for any reply.


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You would not call it dynamics but rather sampling if it was Monte Carlo… So yes MD

Thank you for the prompt reply Dr Bonvin!