# How to interpret HADDOCK score?

**URL:** <https://ask.bioexcel.eu/t/how-to-interpret-haddock-score/4682>\
**Category:** Uncategorized\
**Created:** [November 20, 2023, 9:29am UTC](https://ask.bioexcel.eu/t/how-to-interpret-haddock-score/4682 "2023-11-20T09:29:10Z")\
**Posts on this page:** 1\
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**Author:** ![Aron\_1226](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/aron_1226/32/918_2.png) [@Aron\_1226](https://ask.bioexcel.eu/u/Aron_1226)\
**Post date:** [November 20, 2023, 9:29am UTC](https://ask.bioexcel.eu/t/how-to-interpret-haddock-score/4682/1 "2023-11-20T09:29:10Z")

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Good day, I am an undergraduate and doing a protein-protein docking, I conducted to trial with my proteins, and I am having a hard time interpreting the result that I have obtained, is this a good or bad result? I’ve already tried to read the available literature, yet I can’t find information about what is a bad and good HADDOCK result. Thank you in advance!

Trial 1:  
HADDOCK score -42.7 +/- 23.5  
Cluster size 3  
RMSD from the overall lowest-energy structure 35.8 +/- 0.1  
Van der Waals energy -47.5 +/- 10.9  
Electrostatic energy -372.1 +/- 121.8  
Desolvation energy 28.8 +/- 5.9  
Restraints violation energy 503.9 +/- 104.5  
Buried Surface Area 2320.1 +/- 573.3  
Z-Score -1.9

Trial 2:  
HADDOCK score -99.4 +/- 4.5  
Cluster size 43  
RMSD from the overall lowest-energy structure 8.8 +/- 0.5  
Van der Waals energy -46.0 +/- 8.5  
Electrostatic energy -447.4 +/- 96.0  
Desolvation energy 30.3 +/- 8.3  
Restraints violation energy 58.0 +/- 20.8  
Buried Surface Area 2568.2 +/- 61.0  
Z-Score -1.4