# How to generate HADDOCK restraints TBL file

**URL:** https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290
**Category:** Uncategorized
**Created:** [May 1, 2023, 2:50pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290 "2023-05-01T14:50:39Z")
**Posts on this page:** 5
**Page:** 1

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### Author: ![pei](https://avatars.discourse-cdn.com/v4/letter/p/a698b9/32.png) [@pei](https://ask.bioexcel.eu/u/pei)
#### Post date: [May 1, 2023, 2:50pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290/1 "2023-05-01T14:50:39Z")

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Hello everyone!

I try to use the ab-initio mode to do the docking.  
Instead of specifying active and passive residues, I need to supply a HADDOCK restraints TBL file.

Could you please post a link to show how to generate a HADDOCK restraints TBL file?  
Thanks!

Pei

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### Author: ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)
#### Post date: [May 1, 2023, 5:52pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290/2 "2023-05-01T17:52:23Z")

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For ab-initio docking no need to upload restraints!

Rather turn on ether the center-of-mass restraints or the random AIR ones

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### Author: ![honoratorv](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/honoratorv/32/672_2.png) [@honoratorv](https://ask.bioexcel.eu/u/honoratorv)
#### Post date: [May 1, 2023, 7:26pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290/3 "2023-05-01T19:26:17Z")

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For anyone else that arrives to this post looking on how to generate restraints to use in HADDOCK, please have a look at [GenTBL](https://bianca.science.uu.nl/gentbl), an online tool to generate ambiguous restraints.

> [@pei](#):
>
> I try to use the ab-initio mode to do the docking.

Indeed for ab initio docking you don’t need restraints, have a look at this link that has information on how to setup without and without information:  
[How to use information about interactions in HADDOCK? – Bonvin Lab](https://www.bonvinlab.org/software/bpg/restraints/#ab-initio-docking)

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### Author: ![pei](https://avatars.discourse-cdn.com/v4/letter/p/a698b9/32.png) [@pei](https://ask.bioexcel.eu/u/pei)
#### Post date: [May 1, 2023, 8:15pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290/4 "2023-05-01T20:15:48Z")

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Thank you amjjbonvin!

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### Author: ![pei](https://avatars.discourse-cdn.com/v4/letter/p/a698b9/32.png) [@pei](https://ask.bioexcel.eu/u/pei)
#### Post date: [May 1, 2023, 8:16pm UTC](https://ask.bioexcel.eu/t/how-to-generate-haddock-restraints-tbl-file/4290/5 "2023-05-01T20:16:22Z")

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Thank you Rodrigo!
