# HADDOCK score or PRODIGY binding affinity in the case of mutation

**URL:** <https://ask.bioexcel.eu/t/haddock-score-or-prodigy-binding-affinity-in-the-case-of-mutation/4481>\
**Category:** Uncategorized\
**Created:** [September 3, 2023, 6:58pm UTC](https://ask.bioexcel.eu/t/haddock-score-or-prodigy-binding-affinity-in-the-case-of-mutation/4481 "2023-09-03T18:58:57Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![deovine](https://avatars.discourse-cdn.com/v4/letter/d/bbce88/32.png) [@deovine](https://ask.bioexcel.eu/u/deovine)\
**Post date:** [September 3, 2023, 6:58pm UTC](https://ask.bioexcel.eu/t/haddock-score-or-prodigy-binding-affinity-in-the-case-of-mutation/4481/1 "2023-09-03T18:58:57Z")

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If I were to choose one best mutation between two, mutation A has better HADDOCK Score but mutation B has better binding affinity obtained from PRODIGY, which aspect should I prioritize in choosing the best mutation?