# For haddock score

**URL:** <https://ask.bioexcel.eu/t/for-haddock-score/3367>\
**Category:** HADDOCK\
**Created:** [December 4, 2021, 7:42pm UTC](https://ask.bioexcel.eu/t/for-haddock-score/3367 "2021-12-04T19:42:30Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![kax009](https://avatars.discourse-cdn.com/v4/letter/k/d07c76/32.png) [@kax009](https://ask.bioexcel.eu/u/kax009)\
**Post date:** [December 4, 2021, 7:42pm UTC](https://ask.bioexcel.eu/t/for-haddock-score/3367/1 "2021-12-04T19:42:30Z")

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If I want to compare the change of A’s affinity to B before and after the activation of A, could I perform docking between unactivated A and B as well as activated A and B and compare their haddock score?

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**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\
**Post date:** [December 5, 2021, 6:46pm UTC](https://ask.bioexcel.eu/t/for-haddock-score/3367/2 "2021-12-05T18:46:49Z")

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Hmmm… remember docking scores are not equal to binding affinity…

Never tried something like that. But you could and take the results with a big grain of salt 🙂

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**Author:** ![kax009](https://avatars.discourse-cdn.com/v4/letter/k/d07c76/32.png) [@kax009](https://ask.bioexcel.eu/u/kax009)\
**Post date:** [December 7, 2021, 12:12am UTC](https://ask.bioexcel.eu/t/for-haddock-score/3367/3 "2021-12-07T00:12:18Z")

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Also, for the output parameters (van der waal energy .etc) Where could I read methods about how they are calculated?