# Docking refinement of multimeric structures **URL:** \ **Category:** HADDOCK\ **Created:** [April 11, 2022, 7:02pm UTC](https://ask.bioexcel.eu/t/docking-refinement-of-multimeric-structures/3662 "2022-04-11T19:02:16Z")\ **Posts on this page:** 3\ **Page:** 1
**Author:** ![LucianoPenaTejo](https://avatars.discourse-cdn.com/v4/letter/l/e19b73/32.png) [@LucianoPenaTejo](https://ask.bioexcel.eu/u/LucianoPenaTejo)\ **Post date:** [April 11, 2022, 7:02pm UTC](https://ask.bioexcel.eu/t/docking-refinement-of-multimeric-structures/3662/1 "2022-04-11T19:02:16Z")
I am trying to refine a complex that has 2 coupled proteins, the receptor (4 chains) and the ligand (5 chains). However, HADDOCK only provides the option to select 1 chain for each protein, so that I only get these 2 chains as a result in a PDB file and I require the complete model, that is, the 2 proteins with all their chains. I am following the protocol outlined at [LightDock+HADDOCK membrane proteins tutorial – Bonvin Lab](https://www.bonvinlab.org/education/HADDOCK24/LightDock-membrane-proteins/) Does anyone know if it is possible to do what I need? Beforehand thank you very much, Luciano Talca, Chile ---
**Author:** ![amjjbonvin](https://dub1.discourse-cdn.com/flex013/user_avatar/ask.bioexcel.eu/amjjbonvin/32/23_2.png) [@amjjbonvin](https://ask.bioexcel.eu/u/amjjbonvin)\ **Post date:** [April 11, 2022, 7:24pm UTC](https://ask.bioexcel.eu/t/docking-refinement-of-multimeric-structures/3662/2 "2022-04-11T19:24:15Z")
Try to submit the full model to the haddock2.4 refinement server. ``` https://wenmr.science.uu.nl/haddock2.4/refinement/1 ``` ---
**Author:** ![LucianoPenaTejo](https://avatars.discourse-cdn.com/v4/letter/l/e19b73/32.png) [@LucianoPenaTejo](https://ask.bioexcel.eu/u/LucianoPenaTejo)\ **Post date:** [April 11, 2022, 7:46pm UTC](https://ask.bioexcel.eu/t/docking-refinement-of-multimeric-structures/3662/3 "2022-04-11T19:46:29Z")
Thank you very much, I will try and write here how it went!