# Docking of glycopeptide to antibody

**URL:** https://ask.bioexcel.eu/t/docking-of-glycopeptide-to-antibody/3092
**Category:** HADDOCK
**Created:** [June 10, 2021, 12:00am UTC](https://ask.bioexcel.eu/t/docking-of-glycopeptide-to-antibody/3092 "2021-06-10T00:00:10Z")
**Posts on this page:** 1
**Page:** 1

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### Author: ![OLAF](https://avatars.discourse-cdn.com/v4/letter/o/73ab20/32.png) [@OLAF](https://ask.bioexcel.eu/u/OLAF)
#### Post date: [June 10, 2021, 12:00am UTC](https://ask.bioexcel.eu/t/docking-of-glycopeptide-to-antibody/3092/1 "2021-06-10T00:00:10Z")

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Dear Prof. Bonvin, I tried to dock a glyco-peptide to an antibody using HADDOCK 2.4-web. The result shows that the glycan linkage was broken and each sugar residue was blown out. The glycan structure is Sia-Gal-GalNAc attached to Thr residue of the ligand peptide. Is such glycopeptide supported in HADDOCK 2.4-web? It seems that sugar residue was not recognized by the system and the glycan part was shown as “XXX”. Any information is welcome to get a result. Thanking you in advance.