# Docking membrane ions and water

**URL:** <https://ask.bioexcel.eu/t/docking-membrane-ions-and-water/315>\
**Category:** HADDOCK\
**Created:** [March 10, 2017, 2:45pm UTC](https://ask.bioexcel.eu/t/docking-membrane-ions-and-water/315 "2017-03-10T14:45:35Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Joao\_Fernandes](https://avatars.discourse-cdn.com/v4/letter/j/c68b51/32.png) [@Joao\_Fernandes](https://ask.bioexcel.eu/u/Joao_Fernandes)\
**Post date:** [March 10, 2017, 2:45pm UTC](https://ask.bioexcel.eu/t/docking-membrane-ions-and-water/315/1 "2017-03-10T14:45:35Z")

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I’ll explain what I do, in case someone has a solution to my problem.  
I am trying to perform a docking protein-protein, where, a membrane protein arranged in a lipid membrane and balanced with water and ions, should be bound to a protein.  
I need to know how much these structures interfere with docking.

Any tips?