We are glad to announce the release of our DISVIS webserver.
DisVis allows you to visualizes and quantify the information content of distance restraints between macromolecular complexes. It performs a full and systematic 6 dimensional search of the three translational and rotational degrees of freedom to determine the number of complexes consistent with the restraints. In addition, it outputs the percentage of restraints being violated and a density that represents the center-of-mass position of the scanning chain corresponding to the highest number of consistent restraints at every position in space.
In the context of integrating modelling, this tool should be particularly useful to assess the information content and reliability of cross-links detected by mass spectrometry.
Read more in the original publication.
DISVIS is also freely available for local installation through our GitHub repository: https://github.com/haddocking/disvis
The DISVIS web server is powered by the EGI grid resources.